hSMG-1 inhibitor 11j
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-124719-5 mg |
| CAS # | 1402452-15-6 |
| Pricing | 5 mg, USD $500.0 |
| Biological Activity | hSMG-1 inhibitor 11j, a pyrimidine derivative, is a potent and selective inhibitor of hSMG-1, with an IC50 of 0.11 nM. hSMG-1 inhibitor 11j exhibits >455-fold selectivity for hSMG-1 over mTOR (IC50=50 nM), PI3Kα/γ (IC50=92/60 nM) and CDK1/CDK2 (IC50=32/7.1 μM). hSMG-1 inhibitor 11j can be used for the research of cancer[1]. |
| Purity | 98.91% |
| MWt | 566.07 |
| Formula | C₂₇H₂₈ClN₇O₃S |