Toll/interleukin-1 Receptor Domain-Containing Adapter Protein (TIRAP) Antibody
TIRAP Antibody is a Rabbit Polyclonal antibody against TIRAP. The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
Supplier | Abbexa Ltd. |
---|---|
Product # | abx001586-200UL |
Pricing | 200 µl USD $696.0 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | IHC |
UniProt Primary AC | P58753-1 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |