Arachidonic Acid-[13C5]

Labelled Arachidonic acid. Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules.

• Supplier: BOC Sciences
• Product #: BLP-003333
• Molecular Weight: 309.43
• Molecular Formula: C15[13C]5H32O2
• Canonical SMILES: CCCCCC=CCC=CCC=CCC=CCCCC(=O)O