C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

C24:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. It is the predominate sulfatide species in mature myelin, and it accumulates at a higher rate than C24 3'-sulfo galactosylceramide in rat cerebellum. It is an immunodominant species in myelin, is bound by CD1d in vitro, and increases proliferation in isolated mouse splenocytes. C24:1 3'-sulfo Galactosylceramide can reduce symptoms and increase survival in a mouse model of chronic relapsing-remitting experimental autoimmune encephalomyelitis (EAE) when used at a dose of 20 µg. It also decreases the number of inflammatory lesions and infiltrating mononuclear cells in the lumbar spinal cord of EAE mice.

• Supplier: BOC Sciences
• Product #: 151057-28-2
• Cas: 151057-28-2
• Molecular Weight: 890.30
• Molecular Formula: C48H91NO11S
• Canonical SMILES: O[C@@H]1[C@@H](OS(O)(=O)=O)[C@@H](O)[C@@H](CO)O[C@H]1OC[C@H](NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@H](O)/C=C/CCCCCCCCCCCCC