URB602
URB602 is a selective inhibitor of monoglycerol lipase (MGL), exhibiting an IC50 of 28 µM for the rat brain enzyme. Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats. URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD422 |
| CAS # | 565460-15-3 |
| Pricing | Customizable size, Inquiry |
| Synonym | URB602, URB-602, URB 602 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C19H21NO2 |
| Exact Mass | 295.1572 |
| Molecular Weight | 295.382 |
| Elemental Analysis | C, 77.26; H, 7.17; N, 4.74; O, 10.83 |
| IUPAC/Chemical Name | cyclohexyl [1,1'-biphenyl]-3-ylcarbamate |
| InChi Key | HHVUFQYJOSFTEH-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C19H21NO2/c21-19(22-18-12-5-2-6-13-18)20-17-11-7-10-16(14-17)15-8-3-1-4-9-15/h1,3-4,7-11,14,18H,2,5-6,12-13H2,(H,20,21) |
| SMILES Code | O=C(OC1CCCCC1)NC2=CC(C3=CC=CC=C3)=CC=C2 |
| Appearance | White solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |