JNJ-63576253 free base
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-115282 |
| CAS # | 2110426-27-0 |
| Pricing | inquire |
| Biological Activity | JNJ-63576253 (TRC-253) free base is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 free base can be used for the research of castration-resistant prostate cancer (CRPC)[1]. |
| Synonyms | TRC-253 free base |
| MWt | 502.51 |
| Formula | C₂₃H₂₁F₃N₆O₂S |