TNF-α-IN-2
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-134471-10 mg |
| CAS # | 2074702-04-6 |
| Pricing | 10 mg, USD $850.0 |
| Biological Activity | TNF-α-IN-2 is a potent and orally active inhibitor of tumor necrosis factor alpha (TNFα), with an IC50 of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis[1]. |
| MWt | 494.92 |
| Formula | C₂₅H₂₁ClF₂N₆O |