PROTAC SGK3 degrader-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-125878-10 mg |
| CAS # | 2381320-35-8 |
| Pricing | 10 mg, USD $2250.0 |
| Synonyms | SGK3-PROTAC1 |
| MWt | 1157.38 |
| Formula | C₅₇H₇₃FN₁₀O₁₁S₂ |
| Biological Activity | PROTAC SGK3 degrader-1 (SGK3-PROTAC1), is a potent SKG3 degrader based on PROTAC. PROTAC SGK3 degrader-1 (0.3 μM) induces 50% degradation of endogenous SGK3 within 2 hours, with maximal 80% degradation observed within 8 hours, accompanied by a loss of phosphorylation of NDRG1 (an SGK3 substrate)[1]. |
| Purity | 99.32% |