TP0427736 HCl

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TP0427736 is a potent inhibitor of ALK5 kinase activity with an IC50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC50 = 836 nM for ALK3). It also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with an IC50 value of 8.68 nM.

Supplier	Selleck Chemicals
Product #	S8700
Sku #	S8700-25mg
Pricing	25mg, $790.00

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