| Supplier |
CD Formulation |
| Product # |
PE-0588 |
| Pricing |
, Inquire for price
|
| product1 |
Excipients for Liquid Dosage Form
|
| Molecular Formula |
C54H94O35
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| Molecular Weight |
1303.3
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| Applications |
Widely used in pharmaceutical, food, cosmetics, textiles and other industries. What is remarkable compared to other cyclodextrins is its ability to incorporate oil-soluble molecules.
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| Incompatibilities |
The presence of cyclodextrins in aqueous solutions may reduce the activity of some antibacterial preservatives.
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| Synonyms |
MBC; BETA-CYD; BETA-W7 M18; METHYL B-CYCLODEXTRIN; METHYL-SS-CYCLODEXTRIN; Dimethyl-β-Cyclodextrin; METHYL-BETA-CYCLODEXTRIN; B-Cyclodextrin methyl ether; beta-cyclodextrin, methylethers
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| CAS Number |
128446-36-6
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| Category |
Solubilizing Agents
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| Chemical Name |
/
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| Grade |
Pharmceutical Excipients
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| Source and Preparation |
In this paper, methyl-β-cyclodextrin was prepared by using dimethyl sulfate as alkylation reagent. Add 2g sodium hydroxide and 30mL deionized water to a triangular bottle, then add 10g β-cyclodextrin, stir to dissolve. At room temperature, 5mL dimethyl sulfate was slowly added and stirred at the same time. The reaction was heated in a water bath at about 60 ℃ for 8h. After the reaction, it was cooled and adjusted to neutral with dilute hydrochloric acid. The collection liquid was distilled under vacuum pressure, concentrated to syrupy form, and slowly dropped into 40mL acetone. The product was dispersed into a powdery solid in the acetone. The acetone was filtered out and the product was vacuum dried.
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