BMS-1166 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-102011A |
| CAS # | 2113650-05-6 |
| Pricing | inquire |
| Biological Activity | BMS-1166 hydrochloride is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 hydrochloride induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 hydrochloride antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation[1][2]. |
| MWt | 677.57 |
| Formula | C₃₆H₃₄Cl₂N₂O₇ |