ML 145

Supplier MedChemExpress
Product # HY-107536-10 mM * 1 mL
CAS # 1164500-72-4
Pricing 10 mM * 1 mL, USD $132.0
Biological Activity ML 145 is a selective and competitive human GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM. ML 145 has over 1000-fold more selective for GPR35 compared to GPR55 (IC50/EC50=21.7 μM)[1]. ML 145 has no significant activity for GPR35 at either rodent ortholog[2].
Purity 98.01%
MWt 482.57
Formula C₂₄H₂₂N₂O₅S₂
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