BW 373U86
BW 373U86 is an opioid analgesic drug used in scientific research.[1][2]
BW373U86 is a selective agonist for the δ-opioid receptor, with approximately 15x stronger affinity for the δ-opioid than the μ-opioid receptor. It has potent analgesic and antidepressant effects in animal studies. In studies on rats, BW373U86 appears to protect heart muscle cells from apoptosis in conditions of ischemia (oxygen deprivation, such as in heart attack). The mechanism for this is complex and may be separate from its delta agonist effects.
BW373U86 is a selective agonist for the δ-opioid receptor, with approximately 15x stronger affinity for the δ-opioid than the μ-opioid receptor. It has potent analgesic and antidepressant effects in animal studies. In studies on rats, BW373U86 appears to protect heart muscle cells from apoptosis in conditions of ischemia (oxygen deprivation, such as in heart attack). The mechanism for this is complex and may be separate from its delta agonist effects.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD724 |
| CAS # | 150428-54-9 |
| Pricing | Customizable size, Inquiry |
| Synonym | BW 373U86; BW-373U86; BW373U86 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C27H37N3O2 |
| Exact Mass | 435.2886 |
| Molecular Weight | 435.61 |
| Elemental Analysis | C, 74.45; H, 8.56; N, 9.65; O, 7.35 |
| IUPAC/Chemical Name | 4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-hydroxyphenyl)methyl)-N,N-diethylbenzamide |
| InChi Key | LBLDMHBSVIVJPM-YZIHRLCOSA-N |
| InChi Code | InChI=1S/C27H37N3O2/c1-6-16-29-18-21(5)30(19-20(29)4)26(24-10-9-11-25(31)17-24)22-12-14-23(15-13-22)27(32)28(7-2)8-3/h6,9-15,17,20-21,26,31H,1,7-8,16,18-19H2,2-5H3/t20-,21+,26-/m1/s1 |
| SMILES Code | CCN(C(c1ccc([C@H](c2cc(O)ccc2)N3C[C@H](N(C[C@@H]3C)CC=C)C)cc1)=O)CC |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >3 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |