Human Anti-PCSK9 Recombinant Antibody (clone mAb1)
Recombinant Human Antibody (mAb1) is capable of binding to PCSK9, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-PCSK9 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-PCSK9 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody could block interaction of PCSK9 with the epidermal growth factor-like repeat A domain of LDL receptor (LDLR)
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABL-294 |
| Pricing | Inquiry |
| Host | Human |
| Target | PCSK9 |
| Species Reactivity | Human |
| Type | Human IgG |
| Applications | WB, Block, FuncS |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |