Tracazolate hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-B1803A |
| CAS # | 1135210-68-2 |
| Pricing | inquire |
| Biological Activity | Tracazolate (ICI 136753) hydrochloride is a potent GABAA receptor modulator. Tracazolate hydrochloride has selectivity for β3 and potentiates α1β1γ2s (EC50=13.2 μM), α1β3γ2 (EC50=1.5 μM). Tracazolate hydrochloride has the potency (EC50) determined by the nature of the third subunit (γ1-3, δ, ε) within the receptor complex. Tracazolate hydrochloride possesses anxiolytic and anticonvulsant activity[1][2]. |
| Synonyms | ICI 136753 hydrochloride |
| MWt | 340.85 |
| Formula | C₁₆H₂₅ClN₄O₂ |