Benzamil hydrochloride
Supplier | MedChemExpress |
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Product # | HY-B1546A-50 mg |
CAS # | 161804-20-2 |
Pricing | 50 mg, USD $312.0 |
Synonyms | Benzylamiloride hydrochloride |
MWt | 356.21 |
Formula | C₁₃H₁₅Cl₂N₇O |
Biological Activity | Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+/Ca2+ exchanger (NCX) inhibitor (IC50~100 nM). Benzamil hydrochloride also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca2+-activated currents, with an IC50 of 1.1 μM[1][2][3]. |
Purity | 99.60% |