Peldesine dihydrochloride

Supplier MedChemExpress
Product # HY-106934A-10 mM * 1 mL
Pricing 10 mM * 1 mL, USD $462.0
Synonyms BCX 34 dihydrochloride
MWt 314.17
Formula C₁₂H₁₃Cl₂N₅O
Biological Activity Peldesine (BCX 34) dihydrochloride is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine dihydrochloride is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine dihydrochloride has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research[1][2][3][4].
Purity 99.80%
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