Posovolone
Posovolone, also known as Co 134444, is a GABAA receptor positive allosteric modulator. It is also an antidepressant. Posovolone has anticonvulsant and anxiolytic-like activity as well as ataxic effects.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1091 |
| CAS # | 256955-84-7 (free base) |
| Pricing | Customizable size, Inquiry |
| Synonym | Posovolone; CO-134444; CO-134444; CO134444; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C26H40N2O3 |
| Exact Mass | 428.3039 |
| Molecular Weight | 428.617 |
| Elemental Analysis | C, 72.86; H, 9.41; N, 6.54; O, 11.20 |
| IUPAC/Chemical Name | 1-((3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-3-(methoxymethyl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-(1H-imidazol-1-yl)ethan-1-one |
| InChi Key | BRVGKZNQWCQKTC-MVCIVNJCSA-N |
| InChi Code | InChI=1S/C26H40N2O3/c1-24-10-11-26(30,16-31-3)14-18(24)4-5-19-20-6-7-22(25(20,2)9-8-21(19)24)23(29)15-28-13-12-27-17-28/h12-13,17-22,30H,4-11,14-16H2,1-3H3/t18-,19-,20-,21-,22+,24-,25-,26+/m0/s1 |
| SMILES Code | C[C@@]12[C@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4C(CN5C=CN=C5)=O)([H])C[C@](COC)(O)CC1 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | To be determined |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | To be determined |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |