MRS2365 sodium
MRS2365 is a highly potent and selective P2Y1 receptor agonist (EC50 = 0.4 nM). MRS2365 displays no activity at P2Y12 receptors and only very low agonist activity at P2Y13 receptors (at concentrations up to 1 μM). MRS2365 increases the upregulation of NTPDase1 by ATPγS.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1026 |
| CAS # | MRS2365 sodium |
| Pricing | Customizable size, Inquiry |
| Synonym | MRS2365; MRS 2365; MRS-2365; (N)-methanocarba-2MeSADP; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C13H16N5Na3O9P2S |
| Exact Mass | 548.9837 |
| Molecular Weight | 549.27 |
| Elemental Analysis | C, 28.43; H, 2.94; N, 12.75; Na, 12.56; O, 26.21; P, 11.28; S, 5.84 |
| IUPAC/Chemical Name | [(1R,2R,3S,5S)-4-[6-amino-2-(methylsulfanyl)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexan-1-yl]methyl sodium {[bis(sodiooxy)phosphoryl]oxy}phosphonate |
| InChi Key | ZYPJOXVKTCEBCA-PVMCGCOJSA-K |
| InChi Code | InChI=1S/C13H19N5O9P2S.3Na/c1-30-12-16-10(14)6-11(17-12)18(4-15-6)7-5-2-13(5,9(20)8(7)19)3-26-29(24,25)27-28(21,22)23;;;/h4-5,7-9,19-20H,2-3H2,1H3,(H,24,25)(H2,14,16,17)(H2,21,22,23);;;/q;3*+1/p-3/t5-,7?,8+,9+,13+;;;/m1.../s1 |
| SMILES Code | O=P(OP(OC[C@]12[C@@H](O)[C@@H](O)C(N3C=NC4=C(N)N=C(SC)N=C34)[C@@]1([H])C2)([O-])=O)(O[Na])O[Na].[Na+] |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |