7-Chlorokynurenic acid sodium salt

Supplier MedChemExpress
Product # HY-100811A-10 mM * 1 mL
CAS # 1263094-00-3
Pricing 10 mM * 1 mL, USD $77.0
Synonyms 7-CKA sodium salt
MWt 245.59
Formula C₁₀H₅ClNNaO₃
Biological Activity 7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery[1][2].
Purity 99.79%
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