ERRα antagonist-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-113960-10 mM * 1 mL |
| CAS # | 1072145-33-5 |
| Pricing | 10 mM * 1 mL, USD $94.0 |
| Biological Activity | ERRα antagonist-1 (Compound A) is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively. ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1[1]. |
| Purity | ≥98.0% |
| MWt | 377.53 |
| Formula | C₂₁H₁₉N₃S₂ |