ERRα antagonist-1

Supplier MedChemExpress
Product # HY-113960-10 mM * 1 mL
CAS # 1072145-33-5
Pricing 10 mM * 1 mL, USD $94.0
Biological Activity ERRα antagonist-1 (Compound A) is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively. ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1[1].
Purity ≥98.0%
MWt 377.53
Formula C₂₁H₁₉N₃S₂
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