SM-21 maleate
SM-21 is a potent and selective sigma(2) antagonist. SM-21 is a tropane analogue with high affinity and selectivity for sigma(2) receptor subtype. SM 21 attenuates the convulsive and locomotor stimulatory effects of cocaine in mice. (+/-)-SM 21 may be a suitable lead compound for developing sigma2-selective ligands.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1171 |
| CAS # | 155058-71-2 (racemic free base) |
| Pricing | Customizable size, Inquiry |
| Synonym | SM 21; SM21; SM-21; (±)-SM21; SM-21 maleate; SM-21 racemate maleate, |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C18H24ClNO3 |
| Exact Mass | 337.1445 |
| Molecular Weight | 337.84 |
| Elemental Analysis | C, 63.99; H, 7.16; Cl, 10.49; N, 4.15; O, 14.21 |
| IUPAC/Chemical Name | (1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-(4-chlorophenoxy)butanoate |
| InChi Key | WTPAXDRULIZRDJ-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C18H24ClNO3/c1-3-17(22-15-8-4-12(19)5-9-15)18(21)23-16-10-13-6-7-14(11-16)20(13)2/h4-5,8-9,13-14,16-17H,3,6-7,10-11H2,1-2H3 |
| SMILES Code | CCC(OC1=CC=C(Cl)C=C1)C(O[C@H]2C[C@H](N3C)CC[C@H]3C2)=O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |