7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one is an intermediate of Gefitinib. Gefitinib is an antineoplastic drug. Gefitinib effectively inhibits all tyrosine phosphorylation sites on EGFR in both the high and low EGFR-expressing cell lines including NR6, NR6M and NR6W cell lines. The phosphorylation sites Tyr1173 and Tyr992 are less sensitive requiring higher concentrations of Gefitinib for inhibition.
| Supplier | BOC Sciences |
|---|---|
| Product # | 199327-61-2 |
| Pricing | Inquire |
| Cas | 199327-61-2 |
| Molecular Weight | 319.36 |
| Molecular Formula | C16H21N3O4 |
| Canonical SMILES | COC1=C(C=C2C(=C1)N=CNC2=O)OCCCN3CCOCC3 |