Runt-Related Transcription Factor 2 (RUNX2) Antibody

Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).

• Supplier: Abbexa Ltd.
• Product #: abx033650-400UL
• Clonality: Polyclonal
• Conjugation: Unconjugated
• Host: Rabbit
• Tested Applications: ELISA, WB, IHC, FCM
• UniProt Primary AC: Q13950
• Dry Ice: No
• Availability: Shipped within 5-10 working days.
• Note: This product is for research use only.