N-Desmethyl-Apalutamide
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-135331-5 mg |
| CAS # | 1332391-11-3 |
| Pricing | 5 mg, USD $550.0 |
| Biological Activity | N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration[1][2][3]. |
| MWt | 463.41 |
| Formula | C₂₀H₁₃F₄N₅O₂S |