Afuco™ Anti-Human ITGB7 ADCC Therapeutic Antibody, ADCC Enhanced
Anti-ITGB7 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is a humanized anti-human β7 monoclonal antibody currently in phase I in inflammatory bowel disease. It binds the β7 subunit of the integrins α4β7 and αEβ7, blocking interaction with their ligands. These integrins play key roles in immune cell homing to and retention in mucosal sites, and are associated with chronic inflammatory diseases of the gastrointestinal tract.
| Supplier | Creative Biolabs |
|---|---|
| Product # | AFC-445CL |
| Pricing | Inquiry |
| Host | Humanized |
| Target | ITGB7 |
| Species Reactivity | Human |
| Type | ADCC enhanced antibody |
| Storage | Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C. |