| Supplier |
Creative Peptides |
| Product # |
O06018 |
| Pricing |
Inquire
|
| MolecularWeight |
1713.8
|
| Sequence |
- One Letter Code: RQSVELH-pS-PQSLPR
- Three Letter Code: H-Arg-Gln-Ser-Val-Glu-Leu-His-pSer-Pro-Gln-Ser-Leu-Pro-Arg-OH
|
| Storage |
-20°C
|
| Explanation |
This peptide is a fragment of the human aquaporin-2 (AQP2) phosphorylated at Ser261. Protein phosphorylation plays a key role in vasopressin signaling in renal-collecting duct. Phosphorylation at several AQP2 residues including Ser256 and Ser261, is altered in response to vasopressin. It is possible that both sites are involved in vasopressin-dependent AQP2 trafficking.
|
| Reference |
- 1. Nielsen, S. et al. PNAS 90, 11663 (1993);
- 2. Hoffert, J. et al. PNAS 103, 7159 (2006).
|