PROTAC ER Degrader-4

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PROTAC ER Degrader-4 is a von Hippel-Lindau-based PROATC estrogen receptor (ER) degrader, with an IC50 of 0.8 nM binding to ER. It induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM.

Supplier	BOC Sciences
Product #	2361114-15-8
Pricing	Inquire
Cas	2361114-15-8
Molecular Weight	1005.19
Molecular Formula	C53H67F3N6O8S
Canonical SMILES	CC1CC2=C(C(N1CC(C)(C)F)C3=C(C=C(C=C3F)OCCOCCOCCOCC(=O)NC(C(=O)N4CC(CC4C(=O)NC(C)C5=CC=C(C=C5)C6=C(N=CS6)C)O)C(C)(C)C)F)NC7=CC=CC=C27

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