S-32212 HCl
S-32212 HCl is an inverse agonist of the serotonin (5-HT) receptor subtypes 5-HT2CINI and 5-HT2CVSV. It is also an antagonist of the 5-HT2A receptor and the α2B-adrenergic receptor. S-32212 HCl decreases head twitching, penile erections, and drug discrimination induced by 5-HT receptor agonists in mice and rats. It reduces immobility time in the forced swim test and decreases marble burying in mice and rats indicating anti-depressant-like and anxiolytic activities.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1145 |
| CAS # | 847871-78-7 |
| Pricing | Customizable size, Inquiry |
| Synonym | S-32212 HCl, S32212 HCl, S 32212 HCl |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C25H29ClN4O2 |
| Exact Mass | 452.1979 |
| Molecular Weight | 452.98 |
| Elemental Analysis | C, 66.29; H, 6.45; Cl, 7.83; N, 12.37; O, 7.06 |
| IUPAC/Chemical Name | 1,2-dihydro-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-3H-benz[e]indole-3-carboxamide, monohydrochloride |
| InChi Key | RAKGNVNONBJBSW-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C25H28N4O2.ClH/c1-27-13-15-28(16-14-27)23-17-19(8-10-24(23)31-2)26-25(30)29-12-11-21-20-6-4-3-5-18(20)7-9-22(21)29;/h3-10,17H,11-16H2,1-2H3,(H,26,30);1H |
| SMILES Code | CN1CCN(C2=C(OC)C=CC(NC(N3C(C=CC4=CC=CC=C45)=C5CC3)=O)=C2)CC1.Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >3 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |