GSK163090
GSK163090 is Potent, selective, and orally active 5-HT1A/B/D receptor antagonist. GSK163090 was found to combine potent in vivo activity with a strong preclinical developability profile, and on this basis it was selected as a drug candidate with the aim of assessing its potential as a fast-onset antidepressant/anxiolytic.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD849 |
| CAS # | 844903-58-8 (free base) |
| Pricing | Customizable size, Inquiry |
| Synonym | GSK163090; GSK-163090; GSK 163090. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C25H29N5O |
| Exact Mass | 415.2372 |
| Molecular Weight | 415.541 |
| Elemental Analysis | C, 72.26; H, 7.03; N, 16.85; O, 3.85 |
| IUPAC/Chemical Name | 1-(3-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)phenyl)imidazolidin-2-one |
| InChi Key | ANGUXJDGJCHGOG-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C25H29N5O/c1-19-8-9-22-23(27-19)6-3-7-24(22)29-16-14-28(15-17-29)12-10-20-4-2-5-21(18-20)30-13-11-26-25(30)31/h2-9,18H,10-17H2,1H3,(H,26,31) |
| SMILES Code | O=C1NCCN1C2=CC=CC(CCN3CCN(C4=C5C=CC(C)=NC5=CC=C4)CC3)=C2 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |