CGP 36742
CGP36742 is the first orally active GABAB-selective antagonist. CGP 36742's IC50 for blocking GABAergic transmission is 36 μM. CGP36742 in rats blocks baclofen-induced neuronal depression, and reduces learning deficit and passive avoidance in an olfactory bulbectomy depression model.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD726 |
| CAS # | 123690-78-8 |
| Pricing | Customizable size, Inquiry |
| Synonym | CGP 36742; CGP36742; CGP-36742. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C7H18NO2P |
| Exact Mass | 179.1075 |
| Molecular Weight | 179.2 |
| Elemental Analysis | C, 46.92; H, 10.13; N, 7.82; O, 17.86; P, 17.28 |
| IUPAC/Chemical Name | 3-aminopropyl-butylphosphinic acid |
| InChi Key | ONNMDRQRSGKZCN-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C7H18NO2P/c1-2-3-6-11(9,10)7-4-5-8/h2-8H2,1H3,(H,9,10) |
| SMILES Code | O=P(CCCC)(CCCN)O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |