UNC9994
UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%). UNC9994 has robust in vivo antipsychotic drug-like activities. Functionally selective G protein-coupled receptor (GPCR) ligands, which differentially modulate canonical and noncanonical signaling, are extremely useful for elucidating key signal transduction pathways essential for both the therapeutic actions and side effects of drugs.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1735 |
| CAS # | 1354030-51-5 |
| Pricing | Customizable size, Inquiry |
| Synonym | UNC9994, UNC 9994, UNC-9994 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C21H22Cl2N2OS |
| Exact Mass | 420.083 |
| Molecular Weight | 421.38 |
| Elemental Analysis | C, 59.86; H, 5.26; Cl, 16.83; N, 6.65; O, 3.80; S, 7.61 |
| IUPAC/Chemical Name | 5-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propoxy)benzo[d]thiazole |
| InChi Key | URYZTMIOHYGTNJ-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C21H22Cl2N2OS/c22-18-4-1-3-17(21(18)23)15-7-10-25(11-8-15)9-2-12-26-16-5-6-20-19(13-16)24-14-27-20/h1,3-6,13-15H,2,7-12H2 |
| SMILES Code | ClC1=CC=CC(C2CCN(CCCOC3=CC(N=CS4)=C4C=C3)CC2)=C1Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |