L-152,804
L-152,804 is a potent and selective orally available non-peptide neuropeptide Y Y5 receptor antagonist with Ki value of 26 nM for hY5. It displays > 300-fold selectivity over hY1, hY2, and hY4 receptors. It is centrally active upon oral administration in vivo. It causes weight loss in diet-induced obese mice by inducing a potent reduction of food intake in rodents.
| Supplier | BOC Sciences |
|---|---|
| Product # | 6508-43-6 |
| Pricing | Inquire |
| Cas | 6508-43-6 |
| Molecular Weight | 366.46 |
| Molecular Formula | C23H26O4 |
| Canonical SMILES | CC1(CC(=O)C(C(=O)C1)C2C3=CC=CC=C3OC4=C2C(=O)CC(C4)(C)C)C |