Methyl-CpG Binding Protein 2 (MECP2) Antibody

MECP2 Antibody is a Rabbit Polyclonal antibody against MECP2. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
Supplier Abbexa Ltd.
Product # abx004355-200UL
Pricing 200 µl USD $696.0
Clonality Polyclonal
Conjugation Unconjugated
Host Rabbit
Tested Applications WB
UniProt Primary AC P51608
Dry Ice No
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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