Mutated EGFR-IN-2
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-128860 |
| CAS # | 2050906-97-1 |
| Pricing | inquire |
| Biological Activity | Mutated EGFR-IN-2 (compound 91) is a mutant-selective EGFR inhibitor extracted from patent WO2017036263A1, which potently inhibits single-mutant EGFR (T790M) and double-mutant EGFR (including L858R/T790M (IC50=＜1nM) and ex19del/T790M), and can suppress activity of single gain-of-function mutant EGFR (including L858R and ex19del) as well. Mutated EGFR-IN-2 shows anti-tumor antivity[1]. |
| MWt | 562.64 |
| Formula | C₂₉H₃₅FN₈O₃ |