Recombinant Human SIRPB1 Protein, His-tagged

SIRPB1, also known as signal-regulatory protein beta-1 isoform 1, is a type I transmembrane protein of SIRP superfamily. It is an immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein also participates in the recruitment of tyrosine kinase SYK. And it acts as an activating isoform of SIRP alpha molecules that recruit SHP-1 and SHP-2 protein tyrosine phosphatases and activate counterparts, whose engagement couples to protein tyrosine kinases.

• Supplier: Creative Biomart
• Product #: SIRPB1-001H