Vacuolin-1
Vacuolin-1 is a cell-permeable inhibitor that potently and reversibly inhibits the fusion between autophagosomes and lysosomes in mammalian cells, thereby inducing the accumulation of autophagosomes. Vacuolin-1 is also a PIKfyve inhibitor, which inhibits autophagy by impairing lysosomal maturation via PIKfyve inhibition.
Supplier | BOC Sciences |
---|---|
Product # | 351986-85-1 |
Pricing | Inquire |
Cas | 351986-85-1 |
Molecular Weight | 577.42 |
Molecular Formula | C26H24IN7O |
Canonical SMILES | C1COCCN1C2=NC(=NC(=N2)NN=CC3=CC(=CC=C3)I)N(C4=CC=CC=C4)C5=CC=CC=C5 |