N-Desmethyltamoxifen hydrochloride
Supplier | MedChemExpress |
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Product # | HY-129099A-10 mM * 1 mL |
CAS # | 15917-65-4 |
Pricing | 10 mM * 1 mL, USD $130.0 |
Biological Activity | N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation[1][2][3]. |
Purity | 99.62% |
MWt | 393.95 |
Formula | C₂₅H₂₈ClNO |