C-1311 dihydrochloride
C-1311 is a Fms-like tyrosine kinase 3 inhibitor under the development of Antisoma. It has shown activity in experimental tumour models both in vitro and in nude mice. C-1311 can delay progression of cells through the S phase which was followed by G2 arrest at the EC(99) dose as a mitosis inhibitor. Phase I clinical trials for treatment of solid tumours and a phase II clinical trials for the treatment of breast cancer were discontinued.
| Supplier | BOC Sciences |
|---|---|
| Product # | 138154-55-9 |
| Pricing | Inquire |
| Cas | 138154-55-9 |
| Molecular Weight | 441.35 |
| Molecular Formula | C20H26Cl2N4O3 |
| Canonical SMILES | CCN(CC)CCNC1=C2C3=C(C=C1)N=CN3C4=C(C2=O)C=C(C=C4)O.O.Cl.Cl |