Raloxifene 4'-glucuronide
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-135582 |
| CAS # | 182507-22-8 |
| Pricing | inquire |
| Biological Activity | Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene. Raloxifene 4'-glucuronide formation is mediated mostly by UGT1A10 and UGT1A8. Raloxifene 4'-glucuronide binds to estrogen receptor with an IC50 of 370 μM. [1][2]. Raloxifene is a selective estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression[3]. |
| MWt | 649.71 |
| Formula | C₃₄H₃₅NO₁₀S |