Stauprimide (N-Benzoyl-7-oxostaurosporine, CAS 154589-96-5), >99%

LC Laboratories' Product Number S-9344 - Stauprimide (N-Benzoyl-7-oxostaurosporine, CAS 154589-96-5), >99% - for research use only. Stauprimide increases the efficiency of directed differentiation of mouse and human embryonic stem cells (ESCs). Stauprimide binds to NME2 and inhibits its nuclear localization, thus leading to downregulation of c-Myc. Stauprimide interacts with NME2, a c-Myc-activating transcription factor that is highly expressed in ESCs. Stauprimide treatment inhibits the nuclear localization of NME2 and downregulates c-Myc, enhances ESC exit from the pluripotent state and enables differentiation.

• Supplier: LC Laboratories
• Product #: S-9344
• Sku #: S-9344_1mg