(S,R,S)-AHPC-C2-PEG4-N3
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130654 |
| Pricing | inquire |
| Biological Activity | (S,R,S)-AHPC-C2-PEG4-N3 (VH032-C2-PEG4-N3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-C2-PEG4-N3 can be used in the synthesis of vRucaparib-TP4 (HY-130647). vRucaparib-TP4 a highly potent PARP1 degrader with a half-maximal degrading concentration (DC50) of 82 nM[1]. |
| Synonyms | VH032-C2-PEG4-N3 |
| MWt | 703.85 |
| Formula | C₃₃H₄₉N₇O₈S |