Pepsin A-5 (PGA5) Antibody
PGA5: Pepsinogen 5, group I (pepsinogen A).Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach.Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa.Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus.Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function.Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids.Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates.PGA5 is inhibited by ovUS-1, a uterine serpin.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx015966-100UL |
| Pricing | 100 µl USD $420.5 |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Host | Mouse |
| Tested Applications | ELISA, WB, IHC |
| UniProt Primary AC | P0DJD9 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |