Afuco™ Anti-Human KIR3DL2 ADCC Therapeutic Antibody (IPH41), ADCC Enhanced
Anti-KIR3DL2 ADCC Enhanced Antibody (IPH41) is an ADCC enhanced antibody produced by our Afuco™ platform. IPH41 is a humanized cytotoxic antibody (IgG1) which targets and destroys cells expressing KIR3DL2. KIR3DL2 is an inhibitory receptor of the KIR family, normally expressed on a fraction of normal NK cells but specifically expressed in most subtypes of the orphan indication of cutaneous T-cell lymphomas (CTCL). CTCL is a group of rare cutaneous lymphomas of T lymphocytes with poor prognosis and few therapeutic options at advanced stages.
| Supplier | Creative Biolabs |
|---|---|
| Product # | AFC-449CL |
| Pricing | Inquiry |
| Host | Humanized |
| Target | KIR3DL2 |
| Species Reactivity | Human |
| Type | ADCC enhanced antibody |
| Storage | Short term: store at 4°C (over 6 months), long term: -20°C or -80°C. |