Iptakalim Hydrochloride
Iptakalim is a K(ir) 6.1/SUR2B activator potentially for the treatment of pulmonary arterial hypertension. Iptakalim inhibits PDGF-BB-induced human airway smooth muscle cells proliferation and migration. Iptakalim attenuates hypoxia-induced pulmonary arterial hypertension in rats by endothelial function protection. Iptakalim influences the proliferation and apoptosis of human pulmonary artery smooth muscle cells. Iptakalim activates ATP-sensitive potassium channels in the endothelium of resistance blood vessels.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD924 |
| CAS # | 642407-63-4 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | Iptakalim Hydrochloride |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C9H22ClN |
| Molecular Weight | 179.732 |
| Elemental Analysis | C, 60.14; H, 12.34; Cl, 19.72; N, 7.79 |
| IUPAC/Chemical Name | N-(1-methylethyl)-1,1,2-trimethylpropylamine hydrochloride |
| InChi Key | RXNJQAYLNOXYKW-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C9H21N.ClH/c1-7(2)9(5,6)10-8(3)4;/h7-8,10H,1-6H3;1H |
| SMILES Code | CC(C)C(C)(C)NC(C)C.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |