Recombinant Human Anti-HIV-1 gp120 Antibody (2G12)
Recombinant Human Antibody (2G12) is capable of binding to HIV-1 gp120, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HIV-1 gp120 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-HIV-1 gp120 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This neutralizing human antibody recognizes terminal Man 1-2Man–linked moieties, contributed by oligomannose-type sugars that form a cluster on the silent face of gp120.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABC-062 |
| Pricing | Inquiry |
| Host | Human |
| Target | HIV-1 gp120 |
| Species Reactivity | HIV-1 |
| Type | IgG |
| Applications | Can be useful in applications such as: Neutralization, Enzyme-linked Immunosorbent Assay |
| Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples. |