SCAMP4 (E8Y6Z) Rabbit Antibody

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Supplier CD BioSciences
Product # AMA-0168
Pricing 100 μL, Inquire
Product Category Antibodies
Application WB
Product Usage Information Dilution Western Blotting (1:1000)
Reactivity Human
Host Rabbit
Source/Isotype Rabbit IgG
MW (Target) 25 kDa
Storage Store at -20°C.
Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro30 of human SCAMP4 protein.
Background
  • Secretory carrier membrane proteins (SCAMPs) are a family of conserved integral membrane proteins localized to membranes of the cell-surface recycling system, including secretory organelles and endosomes. SCAMP1, SCAMP2, SCAMP3, and SCAMP4 are ubiquitously expressed, whereas SCAMP5 exhibits primarily neural expression.
  • SCAMP4 protein is enriched on the surface of senescent cells, and its expression regulates the secretion of SASP (senescence-associated secretory phenotype) factors, including interleukin 6 (IL6), IL7, IL8, growth differentiation factor-15 (GDF-15), and C-X-C motif chemokine ligand 1 (CXCL1).
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