Immortalized Mouse Cerebral Capillary Endothelial Cells (cEND)
Immortalized Mouse Cerebral Capillary Endothelial Cells (cEND) from Ace Therapeutics is a specialized cell line developed by immortalizing primary cells using oncoprotein of murine Polyomavirus, Polyoma middle T antigen (PymT). These cell lines share principal features of the BBB in vivo, retaining the endothelial markers VE-Cadherin and PECAM-1, displaying tight junction-associated markers such as occludin, claudin-3, -5, -12, expressing the BBB marker protein Glut-1 and showing high electrical resistance, representing barrier properties. Immortalized Mouse Cerebral Capillary Endothelial Cells (cEND) can serve as a useful model for studies involving the differentiation and regulation of BBB. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | BBM-C-158 |
| Pricing | Inquiry |
| Product Category | Immortalized Cells |
| Species | Mouse |
| Citation Guidance | If you use our product in a scientific publication, please cite it as "Ace Therapeutics Cat.#". Click here to submit your paper's PubMed ID (PMID) to receive rewards. |
| Source | Brain |
| Recommended Medium | It is recommended to use Immortalized Mouse Cerebral Capillary Endothelial Cells (cEND) Medium Kit for culturing in vitro. |
| Cell Type | Endothelial |
| Disease | Normal |
| Quality Control | Immortalized Mouse Cerebral Capillary Endothelial Cells (cEND) test negative for bacteria, yeast, fungi, and mycoplasma. |
| Shipping and Storage |
|