Des-(Pyrazino[2,1-b][1,3]oxazin-2-yl) 4-(3-hydroxy)piperazin-1-yl Venetoclax-M27
Des-(Pyrazino[2,1-b][1,3]oxazin-2-yl) 4-(3-hydroxy)piperazin-1-yl Venetoclax-M27 is an intermediate in the synthesis of Venetoclax-M27 (V121010), a derivative of Venetoclax (ABT 199), which is a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. It's practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.
| Supplier | BOC Sciences |
|---|---|
| Product # | BB068728 |
| Pricing | Inquire |
| Molecular Weight | 884.45 |
| Molecular Formula | C45H50ClN7O8S |