Anti-Human SLC40A1 Therapeutic Antibody (LY2928057)
Recombinant Humanized monoclonal antibody expressed in CHO binding to Human SLC40A1. LY2928057 is a novel humanized IgG4 monoclonal antibody that binds to human ferroportin with a high affinity, blocks the binding of human hepcidin to ferroportin, and is a potent inhibitor of hepcidin activity in a recombinant ferroportin expressing HEK 293 cell-based assay. LY2928057 may provide therapeutic benefit for patients with hepcidin-related anemia by stabilizing ferroportin located on the cell surface, thus restoring iron export and erythropoiesis. LY2928057 is currently in clinical evaluation.
| Supplier | Creative Biolabs |
|---|---|
| Product # | TAB-576CL |
| Pricing | Inquiry |
| Type | Antibody |
| Storage | Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles. |
| Target | SLC40A1 |
| Species Reactivity | Human |